Lipid changes in serum following drug shock and intoxication.

MURATA, K. and NAKAZAWA, K. Lipid Changes in Serum Following Drug Shock and Intoxication. Tohoku J. exp. Med., 1971, 104 (3), 225-232 Serum lipid changes were investigated following a drug shock and 16 intoxication cases. Analyses of serum lipid fractions showed that both drug shock and intoxication resulted in a demonstrable decrease of triglyceride and a trend of increase of phospholipid. The elevated ratio of phospholipid to triglyceride was shown to be closely associated with the severity of the clinical manifestation. It was suggested that the elevation of phospholipid to triglyceride ratio could be used as a feasible index to evaluate and follow cases of shock and intoxication. No appre ciable changes were found in serum hexosamines and cholesterols except in a deceased case in which the latter reduced to less than 70 mg/100 ml. serum lipid; drug shock; intoxication